在3T时使用扩散张力成像来减少宫脊柱植入物周围的金属工件:一个幻影研究
Slimane Tounekti1, Mahdi Alizadeh2, Devon Middleton1
1Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
Magnetic resonance imaging
|November 8, 2023
概括
这项研究引入了一种新的扩散张力成像 (DTI) 方法,结合了降低的视野 (rFOV) 和相段,以最大限度地减少脊髓成像中的金属工件扭曲. 这种技术可以提高金属植入物患者的脊髓完整性评估.
科学领域:
- 医疗成像医学成像
- 神经成像是一种神经成像.
- 生物医学工程 生物医学工程
背景情况:
- 扩散MRI,特别是扩散张力成像 (DTI),对于评估脊髓完整性和手术前损伤至关重要.
- 在手术后获得DTI患者的金属植入物导致显著的几何扭曲,阻碍了准确的评估.
- 现有的DTI技术在脊柱硬件的存在下获得清晰图像方面面临挑战.
研究的目的:
- 开发和验证一种新的DTI获取方法,以克服脊髓成像中的金属诱导的几何扭曲.
- 改善手术后DTI和脊柱植入物患者的纵向治疗评估的可行性.
主要方法:
- 一个定制的幻影模拟宫脊椎与金属植入物被用于DTI数据采集在3特斯拉.
- 拟议的技术,简化的视野相段EPI (rFOV-PS-EPI),与简化的视野单射EPI (rFOV-SS-EPI) 和传统的全FOV方法 (SS-EPI,PS-EPI,RS-EPI) 相比较.
- 图像质量是基于几何扭曲,信号噪声比 (SNR) 和信号空虚等因素进行评估的,统计分析采用两样 t 测试 (p<0.05).
主要成果:
- 与全FOV方法相比,减少FOV技术显示出更高的扭曲减少.
- rFOV-PS-EPI有效地在金属硬件附近产生了DTI图像,其性能优于rFOV-SS-EPI,其距离仅限于~20mm.
- 与rFOV-SS-EPI相比,rFOV-PS-EPI显著降低了几何扭曲 (圆周,离心率;p<0.005) 和信号空隙面积,与传统T2图像没有显著差异.
结论:
- 减少FOV和阶段分割EPI获取的组合是一种高度有效的策略,用于减轻脊柱DTI中金属诱导的扭曲.
- 该技术使得在3特斯拉的脊柱金属硬件存在时可靠的DTI获取成为可能,从而促进了更好的患者评估和治疗监测.
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