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Updated: Jul 11, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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脂肪10被IKKβ酸化以抑制抗病毒I型干扰素反应

Kritika Saxena1, Nicola Domenico Roverato1, Melody Reithmann1

  • 1Department of Biology, Division of Immunology, University of Konstanz, Konstanz, Germany.

Life science alliance
|November 8, 2023
PubMed
概括

通过IKKβ对FAT10的酸化限制了病毒感染和炎症期间有害的I型干扰素 (IFN-I) 生产. 这个过程调节RIG-I信号通路,防止过度的免疫反应和组织损伤.

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