超声波增强剂安全地增强了ECMO支持患者的胸外心声学左心室可视化
Hazem Lashin1, Olusegun Olusanya2, Andrew Smith1
1Adult Critical Care Unit, Barts Heart Centre, St Bartholomew's Hospital, West Smithfield, London, United Kingdom; William Harvey Research Institute, Barts, and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, United Kingdom.
Journal of cardiothoracic and vascular anesthesia
|November 8, 2023
概括
超声增强剂 (UEA) 在体外膜氧化 (ECMO) 患者的胸前心电图 (TTE) 期间显著改善左心室 (LV) 图像质量. 这种改进使得安全测量LV射出分数 (LVEF) 的可行性增加了三倍.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 关键护理医学 关键护理医学
背景情况:
- 胸外回声心电图 (TTE) 对于评估左心室 (LV) 功能至关重要.
- 患者在体外膜氧化 (ECMO) 经常呈现成像挑战.
- 改善ECMO患者的LV图像质量对于及时的临床管理至关重要.
研究的目的:
- 评估超声波增强剂 (UEA) 在通过TTE提高LV图像质量的安全性和有效性.
- 评估UEA对ECMO患者左心室喷射分数 (LVEF) 测量可行性的影响.
- 为了确定UEA是否影响临床或ECMO参数.
主要方法:
- 一项前性研究,涉及18名需要TTE的外围植入ECMO的患者.
- 在注射UEA之前和之后进行的TTE.
- 使用双平面内心边界定义指数和LVEF测量可行性评估LVV图像质量.
主要成果:
- UEA显著改善了LV双平面图像质量,从低于最佳到良好 (p=0.0004).
- 通过TTE测量LVEF的可行性增加了三倍,从25%增加到83% (p=0.0008).
- 没有与UEA相关的不良事件,包括对临床或ECMO参数没有影响.
结论:
- 在ECMO患者的TTE中,UEA安全有效地提高了LV图像质量.
- 通过提高LVEF测量可行性,UEA提高了诊断信心.
- 这种技术为管理ECMO重症患者提供了有价值的工具.
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