没有明显出血的缺铁性贫血患者的小肠病变:一个多中心研究
Angelo Zullo1, Vincenzo De Francesco2, Luigi Gatta3
1Gastroenterology Unit, 'Nuovo Regina Margherita' Hospital, Rome, Italy. angelozullo66@yahoo.it.
Annals of hematology
|November 8, 2023
概括
视频囊内镜 (VCE) 检测到导致缺铁性贫血 (IDA) 的小肠病变,几乎有一半的患者上/下内镜呈阴性. 非类固醇抗炎药物的使用是关键的相关因素.
科学领域:
- 胃肠病学 胃肠病学
- 血液学 血液学 血液学
- 诊断内镜检查 诊断内镜检查
背景情况:
- 当出血或吸收不良不明显时,诊断缺铁性贫血 (IDA) 是复杂的.
- 小肠粘膜病变可能是IDA的潜在原因.
- 标准的上部和下部内镜可能无法识别IDA的来源.
研究的目的:
- 为了确定小肠粘膜病变在IDA患者的患病率.
- 使用视频囊内镜 (VCE) 识别具有高出血潜力的病变 (P2).
- 为了调查与IDA患者的这些病变相关的因素.
主要方法:
- 从5个中心的230名IDA患者的临床和内镜数据的回顾性分析.
- 视频囊内镜 (VCE) 是在负的上部和下部内镜后进行的.
- 识别和计算具有高出血潜力的病变 (P2) 和相关预测因素.
主要成果:
- 在41.7%的IDA患者中,VCE检测到高出血潜力 (P2) 病变.
- 在P2病变中发现了4种 (1.7%) 癌症.
- 非类固醇抗炎药物 (NSAID) 使用是唯一重要的关联因素 (OR: 2.8).
结论:
- 在近一半患有不清楚出血的患者中,VCE有效诊断IDA的原因.
- 小肠粘膜病变是一个重要的,往往未被发现的,IDA的原因.
- 血液学家和胃肠病学家之间的合作改善了IDA的诊断工作.
更多相关视频
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
338
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
338
Assessment of the Rectum and Anus
236
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
236
Inflammatory Bowel Disease II: Crohn's Disease
259
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
259
Chronic Bowel Disorders: Introduction
458
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
458
Histology of the Small Intestine
905
The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
905
Inflammatory Bowel Disease I: Ulcerative Colitis
192
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
192


