在爱尔兰的儿科瘤学中进行治疗性血交换
Dermot M Wildes1, Conor Devlin2, Caoimhe Suzanne Costigan2
1The Department for Paediatric Nephrology & Transplantation, Children's Health Ireland, Dublin, Ireland. dermotwildes@rcsi.com.
Irish journal of medical science
|November 8, 2023
概括
治疗性血交换 (TPE) 是对儿科脏疾病的安全和耐受性良好治疗方法,大多数并发症都是轻微的. 这份对1137个交流的回顾强调了其在专业中心的有效性.
科学领域:
- 儿科脏病学 儿科脏病学
- 传感医学 传感医学
- 脏替代疗法治疗 脏替代疗法
背景情况:
- 治疗性血交换 (TPE) 用于选择儿科脏疾病.
- 关于TPE在儿科患者群体中的数据有限,尽管它已被广泛使用.
- 这项研究回顾了TPE结局和患有病症的儿童的并发症.
研究的目的:
- 评估TPE在患有脏疾病的儿科患者的安全性和有效性.
- 在这个群体中确定TPE的常见指示和相关并发症.
- 评估TPE在儿童中的整体耐受性和不良事件概况.
主要方法:
- 对16岁以下患者的回顾性图表审查.
- 2002年1月至2019年6月在爱尔兰收集的数据.
- 根据病理分层的患者,采用匿名数据提取.
主要成果:
- 58名儿科患者接受了1137次使用氨酸抗凝剂的TPE手术.
- 产生石毒素的大肠杆菌血清性尿素综合征 (STEC-HUS) 是主要的适应症 (n=29).
- 在65.5%的患者中出现并发症,主要是轻微的 (58.6%),无症状低血症是最常见的 (43.1%).
结论:
- 治疗性血交换 (TPE) 是儿童脏护理中安全且耐受良好的疗法.
- 大多数观察到的并发症都是轻微的.
- 在专业中心进行的TPE与不良事件的发病率低相关.
相关概念视频
Acute Kidney Injury V: Interprofessional Care
11
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
11
Continuous Renal Replacement Therapy
38
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
38
Kidney Transplant II: Surgical Procedure
20
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
20
Kidney Transplant I: Introduction
14
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
14
Kidney Transplant III: Nursing Management
22
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
22
Chronic Kidney Disease III: Interprofessional Care
13
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
13


