通过通过CENP-N敲击抑制AKT/mTOR来增强鼻癌细胞的辐射敏感性

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Li-Zhi Wu1, You Zou1, Bin-Ru Wang1

  • 1Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, 238 Jie-Fang Road, Wuhan, 430060, Hubei, People's Republic of China.

Journal of translational medicine
|November 8, 2023
PubMed
概括

减少中心蛋白蛋白N (CENP-N) 通过抑制AKT/mTOR来增强鼻癌 (NPC) 的辐射敏感性. 这种综合方法显著抑制瘤生长,并增加NPC细胞的亡.

关键词:
在 AKT/mTOR 信号通道上.细胞灭亡 (apoptosis) 是一种死亡的过程.在CENP-NN中.细胞循环的细胞周期鼻癌是指鼻癌.辐射敏感性 辐射敏感性

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