在SARS-CoV-2疫苗接种后,有未破裂的视网膜动脉宏动脉瘤的分支视网膜动脉封闭:一个病例报告
Keigo Murata1, Daisuke Nagasato1,2,3, Hayato Tanaka1
1Department of Ophthalmology, Tsukazaki Hospital, Himeji, Hyogo, Japan.
European journal of ophthalmology
|November 9, 2023
概括
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 疫苗接种可能与有视网膜动脉大动脉瘤 (RAM) 患者的分支视网膜动脉堵塞 (BRAO) 有关. 本案例报告强调了需要进一步调查的潜在关联.
科学领域:
- 眼科医生 眼科 眼科
- 疫苗学 疫苗学 疫苗学
- 视网膜血管疾病 视网膜血管疾病
背景情况:
- 在SARS-CoV-2疫苗接种后记录了眼部不良事件.
- 本报告详细介绍了一例罕见的分支视网膜动脉封闭 (BRAO) 病例,该病例发生在接种疫苗后未破裂的视网膜动脉大动脉瘤 (RAM) 患者身上.
研究的目的:
- 报告发生在SARS-CoV-2疫苗接种后的BRAO病例,该病例发生在患有之前存在的RAM的患者中.
- 在易受感染的个体中提高对接种COVID-19疫苗后潜在的眼部并发症的认识.
主要方法:
- 一个75岁的男性患有2型糖尿病的病例研究,并有未破裂的RAM的病史.
- 进行了临床检查, funduscopy,绿色血管造影,光素血管造影和光学连贯性断层扫描血管造影.
- 患者接受了BNT162b2 SARS-CoV-2 mRNA疫苗的第四剂量.
主要成果:
- 接种疫苗后一天,患者在右眼出现了突然的视力丧失,最佳校正视力敏度 (BCVA) 从1.0降至0.7.
- Fundus 检查显示血管内膜的增加.
- 血管造影证实了BRAO在视网膜上部区域,与RAM相关.
结论:
- 这些发现表明,SARS-CoV-2疫苗接种和BRAO在没有破裂的RAM的个体中发展之间的潜在联系.
- 需要进一步的研究来阐明潜在的机制并确认这种关联.
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