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Updated: Jul 11, 2025
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Comparative Lesions Analysis Through a Targeted Sequencing Approach
Published on: November 5, 2019
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清细胞细胞癌与BAP1突变:报告了两个病例
Jennifer Lee1,2, Moe Thuzar1,2, Angela C DiPoto-Brahmbhatt1,2
1Pathology and Laboratory Medicine Service, Overton Brooks VA Medical Center Shreveport, LA, USA.
American journal of clinical and experimental urology
|November 9, 2023
概括
具有BAP1突变的清细胞细胞癌 (RCC) 可以表现出明显的特征和攻击性行为. 这项研究详细介绍了两个这样的病例,强调了癌中独特的组织病理学发现和遗传改变.
科学领域:
- 在瘤学瘤学.
- 遗传学 遗传学 是一个
- 病理学 病理学 病理学
背景情况:
- 清细胞细胞癌 (ccRCC) 是成年人中最常见的癌亚型.
- 在ccRCC中,VHL基因突变很普遍 (>90%),与其他染色体3p瘤抑制剂 (如BAP1,PBRM1和SETD2.2) 一起.
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