在结性脊柱炎患者的斑点跟踪心声学和亚临床参与的评估
Mir Amir Aghdashi1, Amir Mikaeilvand2, Mohammad Mostafa Ansari-Ramandi3
1Department of Rheumatology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
结性脊柱炎患者表现出心脏功能受损,特别是左心室全球纵向应变,表明早期心血管参与. 这种亚临床心肌功能障碍是独立于传统的心血管风险因素观察到的.
科学领域:
- 心脏病学 心脏病学
- 类风湿病学 类风湿病学
- 医疗成像医学成像
背景情况:
- 化脊柱炎 (AS) 是一种慢性炎症性疾病,影响脊柱,关节和潜在的心血管系统.
- 亚临床心肌功能障碍可以使用左心室 (LV) 全球纵向应变 (GLS) 来检测.
研究的目的:
- 评估AS患者的亚临床LV心肌系统功能障碍,无论心血管疾病风险因素如何.
- 在AS患者中确定GLS和大动脉根异常之间的关联.
主要方法:
- 一项涉及28名AS患者和26名健康对照者的病例控制研究.
- 包括斑点跟踪在内的心声学被用于评估LV静脉缩功能 (GLS),大动脉直径和腹功能.
主要成果:
- 与对照组相比,AS患者表现出显著更多的舒张功能障碍 (p=0.009).
- 与对照组相比,在AS患者的三室视图中发现了一种明显受损的纵向菌株.
- 在GLS和大动脉根异常之间没有观察到任何显著的关联.
结论:
- 在AS患者中,纵向应变损伤可能是心血管参与的早期指标.
- 这一发现表明,除了已知的危险因素之外,AS的潜在心脏影响.
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