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抗腹和抗氧化作用的Ajuga iva (L.) 树叶提取物
Mohamed H Ladjimi1, Zaineb Ben Barka1, Karima Lahbib2
1Laboratory of Integrated Physiology UR11S33, Faculty of Science of Bizerte, University of Carthage, 7021 Jarzouna, Tunisia.
Heliyon
|November 9, 2023
概括
该研究发现,Ajuga iva叶提取物 (AIE) 通过作为抗氧化剂和改善肠道健康,有效减少大鼠的腹. 这项研究证实了这种植物在治疗腹方面的传统用途.
科学领域:
- 药理学 药理学是指药理学的学科.
- 自然产品研究自然产品研究
- 胃肠病学 胃肠病学
背景情况:
- 在全球范围内,腹仍然是一个重大的健康问题.
- 传统医学经常利用植物性药物治疗胃肠道疾病.
- 阿朱加伊瓦是一种传统上因其药用特性而被使用的植物.
研究的目的:
- 为了研究Ajuga iva叶子提取物 (AIE) 的抗腹作用.
- 评估AIE在腹期间对肠道吸收,运动性和氧化应激的影响.
- 为Ajuga iva在治疗腹中的传统用途提供科学验证.
主要方法:
- 威斯塔尔老鼠被给予麻油 (CO),以诱导腹.
- 组接受了单独的CO,CO与loperamide,或CO与AIE的不同剂量.
- 分析了肠道参数,包括排便,氧化应激标志物 (GPx,OH°,O2°-,碳蛋白,MDA) 和矿物质含量 (,).
主要成果:
- 国际医学协会 (AIE) 证明了因麻油诱导的腹的剂量依赖性预防.
- 服用800mg/kg的AIE剂量显著抑制了排便和腹.
- 通过增加谷氨过氧化酶活性和减少自由基,碳蛋白和MDA水平,AIE减轻了CO的亲氧化作用.
- AIE的使用导致肠道和含量增加.
结论:
- 阿朱加伊瓦叶提取物具有显著的抗腹活性.
- AIE的治疗效果部分归因于其强大的抗氧化特性.
- 这项研究提供了科学证据,支持Ajuga iva用于治疗腹的传统应用.
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