空气污染颗粒物对缺血性和出血性中风的影响:一个范围审查
Krista Lamorie-Foote1, Brandon Ge2, Kristina Shkirkova2
1Neurological Surgery, University of Southern California, Los Angeles, USA.
Cureus
|November 9, 2023
概括
空气污染颗粒物 (PM) 暴露显著增加缺血性中风风险. 对出血性中风的影响不太清楚,老年人和糖尿病患者最容易受到影响.
科学领域:
- 环境健康 环境健康
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 空气污染颗粒物 (PM) 是已知的中风风险因素.
- 缺血性中风 (IS) 和出血性中风 (HS) 存在明显的病理生理路径.
- 有限的研究探讨了PM对中风亚型的差异性影响.
研究的目的:
- 审查PM暴露对IS和HS的影响.
- 确定易受颗粒物毒性影响的脆弱子群体.
主要方法:
- 在PubMed中搜索 (2000-2023) 临床和流行病学研究.
- 收录标准:英语,明确的定义,PM效应,不同的亚型分析.
- 两位独立审稿人对50篇精选的文章进行了选.
主要成果:
- 在全球范围内,暴露于PM会增加IS风险.
- PM与HS风险的关联是可变的,可能取决于污染水平.
- 老年人和糖尿病患者显示出更强烈的PM中风相关性.
结论:
- 暴露于颗粒物增加了IS风险;其对HS风险的影响需要进一步调查.
- 老年人和患有糖尿病的人特别容易受到颗粒物毒性的影响.
- 未来的研究应该澄清性别和高血压对PM相关中风风险的影响.
相关概念视频
Peripheral Artery Disease I: Introduction
9
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs but also impacts other areas, such as the arms, thereby impairing overall circulation and organ function.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty deposits inside the arterial...
9
Ischemic Heart Disease: Overview
1.3K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.3K


