瘤学中的药基因组测试:卫生系统的方法来确定瘤学提供者的观点
Meghna Bhatt1, Beth N Peshkin2, Sadaf Kazi1,3
1MedStar Health, Columbia, MD 21044, USA.
Pharmacogenomics
|November 9, 2023
概括
瘤学提供者认识到药物基因组测试 (PGx) 的好处,以改善患者护理和药物处方. 增加的PGx教育与更高的测试排序相关,表明实施机会.
科学领域:
- 药物基因组学 药物基因组学
- 在瘤学瘤学.
- 临床药房 临床药房
背景情况:
- 药物遗传学 (PGx) 测试有可能个性化癌症治疗和支持性护理.
- 了解瘤学提供者对PGx障碍和用例的看法对于实施至关重要.
研究的目的:
- 评估瘤医疗保健提供者对药物基因组测试的态度.
- 确定PGx测试在处方抗癌和支持性护理药物的障碍和用例.
主要方法:
- 在MedStar健康系统中,向瘤医疗提供者发放了一份问卷.
- 从25个符合条件的瘤医疗机构收集了与PGx测试相关的认识,信念和订购实践的数据.
主要成果:
- 88%的医疗服务提供者知道PGx测试,而72%的人认为它可以改善患者护理.
- 最近订购相关药物的提供者报告了对抗癌症和支持性护理药物的PGx的高度兴趣.
- 之前的PGx教育显著增加了订购PGx测试的可能性 (OR:7.9,p=0.0394).
结论:
- 瘤医疗服务提供者对利用PGx测试表现出显著的认识和兴趣.
- 提供者教育是促进在临床实践中采用PGx测试的关键因素.
- 这些发现突出了实施PGx测试以优化癌症护理和药物管理的机会.
相关概念视频
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Analysis of Population Pharmacokinetic Data
267
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
267
Issues And Trends In Healthcare Delivery System
5.6K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.6K
Biopharmaceutics and Pharmacokinetics: Overview
2.1K
Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
2.1K


