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Updated: Jul 11, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
11:45

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

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怀克辛辛A的合成:探索九个成员环形形成的策略

Christian Steinborn1, Tatjana Huber2, Julian Lichtenegger1

  • 1Institute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.

Chemistry (Weinheim an der Bergstrasse, Germany)
|November 9, 2023
PubMed
概括

研究人员详细介绍了waixenicin A的合成,克服了使用新策略构建其复杂的九个环的挑战,并实现了关键的中间构成.

关键词:
自然产品是自然产品的产品.有九个成员的戒指.化物是一种化物.总合成总合成这种药物是 xenicins.

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Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation

Robinson annulation is a base-catalyzed reaction for the synthesis of 2-cyclohexenone derivatives from 1,3-dicarbonyl donors (such as cyclic diketones, β-ketoesters, or β-diketones) and α,β-unsaturated carbonyl acceptors. Named after Sir Robert Robinson, who discovered it, this reaction yields a six-membered ring with three new C–C bonds (two σ bonds and one π bond).
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