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Updated: Jul 11, 2025

Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms
06:40

Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms

Published on: January 25, 2018

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分子动力学 γ-分泌酶的激活,用于切割 Notch1 基质

Hung N Do, Shweta R Malvankar, Michael S Wolfe

    ACS chemical neuroscience
    |November 9, 2023
    PubMed
    概括

    这项研究揭示了马分泌酶如何使用分子动力学模拟来切割Notch蛋白. 研究人员开发了准确的模型,显示了Notch裂变的马分泌酶相互作用,从而进一步了解了这种蛋白酶复合物的理解.

    关键词:
    斯加速分子动力学免费能源的个人资料.膜内蛋白质溶解是一种内膜蛋白质.质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量

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