在神经元自性溶酶体改造中对RME-8/DNAJC13的保存要求

Sierra B Swords1, Nuo Jia2, Anne Norris1

  • 1Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ, USA.

Autophagy
|November 9, 2023
PubMed
概括

在神经元中,RME-8/DNAJC13蛋白对自性溶酶体重构 (ALR) 起着至关重要的作用. 丢失RME-8/DNAJC13会导致延长的自身溶解体管道,并影响神经元健康,可能影响神经退行性疾病.

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