[有机性喘息障碍儿童的认知障碍]
L S Chutko1, S Yu Surushkina1, E A Yakovenko1
1N. Bekhtereva Institute of Human Brain Russian Academy of Sciences, St. Petersburg, Russia.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
|November 9, 2023
概括
Cogitum有效地治疗儿童的有机喘息障碍,改善注意力和记忆力等认知功能. 神经生理学研究表明,治疗后大脑活动增加.
科学领域:
- 儿科神经学 儿科神经学
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 儿童有机喘息障碍表现为认知障碍和独特的神经生理学特征.
- 了解这些特征对于有效的治疗干预至关重要.
研究的目的:
- 研究被诊断患有有机性喘息障碍的儿童的认知缺陷和神经生理学标志物.
- 评估Cogitum在治疗这些障碍方面的疗效.
主要方法:
- 一项涉及40名有机性喘息障碍儿童 (8-10岁) 和30名对照儿童的研究.
- 使用了测量喘息严重程度和认知速度缓慢的尺度,工作记忆测试,注意力/冲动性评估 (TOVA) 和电脑电图 (EEG).
- 治疗组接受了Cogitum (30天每天10毫升).
主要成果:
- 患有有机性喘息障碍的儿童表现出工作记忆减少,认知节奏缓慢增加,注意力不集中/冲动性更高.
- 脑电图显示,前部中部区域的α和θ波功率增加.
- 在治疗后,77.5%的患者表现出减轻了喘息,改善了认知功能,EEG模式正常化,表明新皮层活化增加.
结论:
- 认知治疗显著缓解了儿童的喘息和认知障碍.
- 该药物增强了大脑的功能状态,通过提高认知表现和正常化的神经生理标记来证明这一点.
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