在杀菌过程中使用生物指标检测过热蒸汽
Biomedical instrumentation & technology
|November 9, 2023
概括
快速读取的独立生物指标 (RRSCBIs) 可以检测超热蒸汽 (SHS),一种微生物杀伤性较低的灭菌剂. 然而,检测的有效性取决于RRSCBIs在灭菌周期中的方向.
科学领域:
- 消毒科学是消毒科学.
- 微生物学 微生物学
- 医疗器械再加工 医疗器械再加工
背景情况:
- 和蒸汽 (SS) 是医疗器械灭菌的标准,创造了一个杀菌环境.
- 超热蒸汽 (SHS),加热超过其和点,是不那么微生物杀伤性和危害绝育效率.
- 有效的灭菌监测系统对于检测像SHS这样的偏差至关重要.
研究的目的:
- 评估快速读取独立生物指标 (RRSCBIs) 检测超热蒸汽 (SHS) 的能力.
主要方法:
- 在BI评估电阻计中,RRSCBIs在受控条件下暴露于和蒸汽 (SS) 和过热蒸汽 (SHS).
- 在名义121.75°C和132.5°C循环时,SHS可重复地达到大约12°C或4.5°C的超热.
- RRSCBIs在垂直,倒置和水平方向下进行了测试,并通过光读出评估了可行性.
主要成果:
- 暴露于SS的RRSCBIs呈阴性,证实了循环疗效.
- RRSCBIs检测到SHS,但检测率随着方向而有显著差异.
- 当RRSCBIs放置水平或倒置时,与垂直相比,观察到更高的SHS检测率.
结论:
- 在灭菌过程中,RRSCBIs可以作为超热蒸汽的检测方法.
- RRSCBIs的定位是影响其检测SHS的能力的一个关键因素.
- 需要进一步的研究来优化RRSCBI的使用和在临床环境中解释发现.
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