hnRNPA1 SUMOylation通过稳定TRPA1 mRNA来促进慢性炎症性疼痛中的感冒过敏

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Qiao Zhang1, Weiji Weng1, Xiaokun Gu1

  • 1Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Cell reports
|November 9, 2023
PubMed
概括

hnRNPA1的SUMOylation增强TRPA1mRNA的稳定性,增加TRPA1的表达,并导致炎症性感冒疼痛过敏. 这突出了hnRNPA1作为慢性疼痛发展的关键调节者.

关键词:
科普:神经科学是什么意思在TRPA1表达式中,在慢性炎症性疼痛中的感冒过敏.在 hnRNPA1 SUMOylation 中进行.在mRNA的稳定性上.

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