Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

179
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
179
CNS Stimulants: Psychedelic Agents01:22

CNS Stimulants: Psychedelic Agents

158
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
158
An Overview of Psychoactive Drugs01:28

An Overview of Psychoactive Drugs

236
Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
236
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

206
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
206
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

104
Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
104
Stimulants01:29

Stimulants

220
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
220

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Mapping the mammalian dark metabolome by <i>in vivo</i> isotope tracing.

bioRxiv : the preprint server for biology·2026
Same author

Comprehensive Curation and Harmonization of Small-Molecule MS/MS Libraries in Spectraverse.

Analytical chemistry·2026
Same author

Language model-guided anticipation and discovery of mammalian metabolites.

Nature·2026
Same author

Unbiased discovery of neuronal architectures.

Science (New York, N.Y.)·2025
Same author

A neuronal architecture underlying autonomic dysreflexia.

Nature·2025
Same author

A clinical road map for single-cell omics.

Cell·2025
Same journal

Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

Science (New York, N.Y.)·2026
Same journal

Local signals, systemic decline.

Science (New York, N.Y.)·2026
Same journal

The mechanics of liver regeneration.

Science (New York, N.Y.)·2026
Same journal

Computing in a memory with physics.

Science (New York, N.Y.)·2026
Same journal

Retraction.

Science (New York, N.Y.)·2026
Same journal

Making time.

Science (New York, N.Y.)·2026
查看所有相关文章

相关实验视频

Updated: Jul 11, 2025

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
07:30

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice

Published on: July 9, 2016

7.3K

产生幻觉的幻觉剂

Michael A Skinnider1,2

  • 1Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.

Science (New York, N.Y.)
|November 9, 2023
PubMed
概括
此摘要是机器生成的。

创造性人工智能 (AI) 提供了一种新的方法来对抗日益增长的设计药物流行. 这项技术有助于识别和减轻与新型精神活性物质相关的风险.

更多相关视频

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

11.6K
Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

6.7K

相关实验视频

Last Updated: Jul 11, 2025

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
07:30

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice

Published on: July 9, 2016

7.3K
Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

11.6K
Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

6.7K

科学领域:

  • 毒品政策
  • 人工智能
  • 法医化学

背景情况:

  • 设计制药的兴起是一个重大的公共卫生挑战.
  • 传统的识别和控制新精神活性物质的方法往往被快速的化学创新所超越.

研究的目的:

  • 探索创造性人工智能 (AI) 在应对设计药物流行中的潜力.
  • 研究人工智能驱动的早期检测和干预策略.

主要方法:

  • 使用生成性AI模型预测新兴设计药物的化学结构.
  • 使用人工智能快速分析法医数据和在线市场趋势.
  • 开发基于人工智能的新型精神活性物质风险评估工具.

主要成果:

  • 基于现有的化学支架,生成性AI可以快速识别潜在的新型精神活性物质.
  • 人工智能模型在预测药物特性和潜在危害方面具有很高的准确性.
  • 通过人工智能分析显著提高了设计药物趋势的早期检测.

结论:

  • 创造性人工智能为公共卫生和执法机构提供了强大的新工具.
  • 人工智能驱动的方法可以主动打击设计药物流行.
  • 持续开发和实施人工智能对于减轻与毒品有关的危害至关重要.