墨西哥的Fusariosis:一个10年的回顾系列
Armando Barragán-Reyes1, Luis Esaú López Jácome2, Diana Perales-Martínez3
1Hospital Médica Sur, Internal medicine department, Mexico City, Mexico.
Medical mycology
|November 9, 2023
概括
体感染 (体病) 在墨西哥是一个严重的威胁,特别是在烧伤患者和血液恶性瘤患者中. 这项研究强调了对这些机会性真菌感染的更大认识和管理的需要.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 临床医学 临床医学
背景情况:
- 类物种是机会性真菌病原体,在墨西哥的人类感染记录有限.
- 墨西哥关于菌病的数据很少,需要进行本地流行病学研究.
研究的目的:
- 为了回顾分析2010年至2019年期间在墨西哥发生的菌病例.
- 为了确定风险因素,临床表现,治疗模式和墨西哥患者队列中fusarosis的结果.
主要方法:
- 在墨西哥八家医院 (从2010年1月到2019年12月) 诊断出有菌病的49名患者的回顾性病例系列.
- 使用欧洲癌症和真菌菌研究小组教育和研究联盟 (EORTC/MSCG) 标准确认了诊断.
- 收集关于患者人口统计,潜在疾病,损伤类型,临床综合征,治疗方法和死亡率的数据.
主要成果:
- 烧伤 (49%) 和血液恶性瘤 (37%) 是最常见的诱导因素.
- 皮肤和软组织的感染 (49%) 是最常见的,其次是血液,肺部,鼻腔,骨和眼睛的感染.
- 沃里康纳 (30%) 和常规的安福特里辛B (16%) 是常见的单一疗法;组合疗法在20%使用.
- 与Fusarium感染相关的死亡率为22%.
结论:
- 病在墨西哥构成重大威胁,烧伤和血液恶性瘤是主要的危险因素.
- 有效的管理策略和提高临床警对于改善结果至关重要.
- 需要进行进一步的研究,以了解该地区的流行病学和优化菌病的治疗.
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