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Updated: Jul 11, 2025

Incorporating Target Protein Structure Flexibility and Dynamics in Computational Drug Discovery Using Ensemble-Based Docking Analysis
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康多克:一种新的蛋白质-蛋白质对接方法,具有高效的融合策略

Qiaozhen Meng1, Fei Guo2, Ercheng Wang3

  • 1College of Intelligence and Computing, Tianjin University, Tianjin, China.

Computers in biology and medicine
|November 9, 2023
PubMed
概括

本研究介绍了ComDock,这是一种新的计算方法,它结合了基于模板和ab initio的方法,以实现精确的蛋白质-蛋白质对接. 康多克改进了蛋白质复杂结构的预测,有助于理解生物通路和药物发现.

关键词:
蛋白质与蛋白质的对接基于模板的基于模板的模板.在 ZDOCK 中使用.

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