利用疫苗接种后的时代:新出现的HPV类型是否构成新的威胁?
Sergio Ponce-de-Leon1, Marcela Lizano2
1Unidad de Epidemiología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Col. Belisario Domínguez, Tlalpan, Mexico City 14080, Mexico.
Cell host & microbe
|November 9, 2023
概括
人类乳头瘤病毒 (HPV) 疫苗是有效的,但这项研究调查了其他HPV类型是否可能成为威胁. 研究人员在接种疫苗8年后分析HPV类型后,没有发现这种证据.
科学领域:
- 流行病学 流行病学
- 病毒学 病毒学
- 公共卫生 公共卫生
背景情况:
- 人类乳头瘤病毒 (HPV) 疫苗在预防感染方面非常有效.
- 人们对疫苗接种后非向型HPV类型可能占据利基存在担忧.
- 在接种疫苗政策之后,对HPV类型分布的长期流行病学数据有限.
研究的目的:
- 分析HPV疫苗接种对HPV类型分布的社区级流行病学影响.
- 调查非向型HPV类型作为威胁的潜力.
- 为了评估HPV类型动态,在实施不同疫苗接种策略后的8年内.
主要方法:
- 社区一级的流行病学分析.
- 长度研究设计跟踪HPV类型.
- 对8年后疫苗接种政策数据的分析.
主要成果:
- 该研究没有发现非向型HPV类型出现以填补疫苗向型留下的空白的证据.
- HPV 类型的分布保持稳定,而以前不常见的类型没有显著增加.
- 这些发现表明,HPV疫苗不会导致其他HPV类型的补偿性增加.
结论:
- HPV 疫苗似乎并没有为其他 HPV 类型的出现创造生态.
- 目前的疫苗接种政策与非向型HPV类型的风险增加无关.
- 在病毒生态学方面,HPV疫苗的长期安全性和有效性得到了这些发现的支持.
相关概念视频
Cancer Vaccines
380
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
380
Vaccinations
44.6K
Overview
44.6K
Mechanisms of Retrovirus-induced Cancers
5.1K
Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
5.1K
Rous Sarcoma Virus (RSV) and Cancer
5.1K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
5.1K
Skin Cancer
4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
Immunological Memory
630
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
630


