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Updated: Jul 11, 2025

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口腔吸入的Ag/TiO2纳米混合体:转化,分布和毒性

Xiaoquan Huang1, Congcong Li1, Tingting Wei1

  • 1Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, PR China.

The Science of the total environment
|November 9, 2023
PubMed
概括

吸入含有银的二氧化 (Ag/TiO2) 纳米混合物可能会造成肺部暴露的风险. 虽然释放的白银分布到其他器官,但肺部仍然是主要的毒性目标,表现出炎症和纤维化.

关键词:
带有Ag的TiO(2) 纳米粒子.生物分布 生物分布生物转化 生物转化在纳米复合材料.纳米毒性 纳米毒性

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When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
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