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Updated: Jul 11, 2025

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热冲击因子1驱动调节性T细胞诱导,以限制小鼠肠道炎症

Colm B Collins1, Tom T Nguyen2, Robert S Leddy3

  • 1Mucosal Inflammation Program University of Colorado, Anschutz Medical Campus, Aurora, CO, USA; Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition University of Colorado, Anschutz Medical Campus, Aurora, CO, USA; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

Mucosal immunology
|November 9, 2023
PubMed
概括

热冲击因子1 (HSF1) 在炎症期间促进调节性T细胞 (Treg) 发育和功能. 缺少HSF1会损害Tregs,而过度表达会增强Treg抑制能力,并防止肠道炎症.

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