丹麦全国性关于手术治疗感染性原生腹腔大动脉动脉瘤的研究
Rebecca A C Skov1, Martin Lawaetz2, Nikolaj Eldrup3
1Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; Copenhagen Academy for Medical Education and Simulation (CAMES), Denmark.
概括
感染性本源性大动脉动脉瘤 (INAA) 的手术治疗增加,血管内大动脉修复 (EVAR) 显示的生存率与开放性手术修复 (OSR) 相当. 在这个丹麦队列中,术后感染相关的并发症并不常见.
科学领域:
- 血管外科 血管外科
- 传染性疾病 传染性疾病
- 大动脉动脉瘤治疗方法
背景情况:
- 传染性原生大动脉动脉瘤 (INAA) 是一种罕见但严重的疾病,需要手术干预.
- 了解手术趋势和结果对于优化患者管理至关重要.
研究的目的:
- 在丹麦患者中描述INAAs的手术趋势,生存率和与感染有关的并发症 (IRC).
- 为了比较开放外科修复 (OSR) 和内血管大动脉修复 (EVAR) 之间的结果.
主要方法:
- 在丹麦进行手术治疗的INAA患者 (2000-2020) 的回顾性全国性队列研究.
- 数据来源于丹麦血管登记 (Karbase) 和电子患者病历.
- 分析包括临床表现,治疗,死亡率和并发症.
主要成果:
- 包括75名患者 (80%是男性,中位数年龄为69岁); 72%的OSR,28%的EVAR.
- 总体30天的生存率为97%. 10年的长期存活率为48%.
- EVAR的长期存活率与OSR的长期存活率相似,短期存活率高达5年. 败血症是导致死亡的主要原因. IRC的发病率很低 (9%的OSR与5%的EVAR相比).
结论:
- 在研究期间,INAA的手术治疗增加了.
- 对于INAAs,EVAR提供了与OSR相似的长期存活率,手术后IRC的发病率很低.
- 建议未来的注册表进行进一步的验证.
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