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Updated: Jul 11, 2025

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
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在Giardia中,酶站刺激的感知由乙酸环酶AC2-依赖的cAMP信号传递中介

Han-Wei Shih1, Germain C M Alas1, Alexander R Paredez2

  • 1Department of Biology, University of Washington, Seattle, WA, 98195, USA.

Nature communications
|November 9, 2023
PubMed
概括

吉亚迪亚兰布里亚细胞突变是由膜变化引发的,这些变化激活了腺酸环酶2 (AC2),导致cAMP水平增加和寄生虫分化. 这项研究阐明了寄生虫的一个关键步骤.

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