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素727的STAT3酸化激活了特定的遗传程序,并促进了清细胞细胞癌 (ccRCC) 的攻击性

J Arévalo1, I Campoy2, M Durán2

  • 1Renal Physiopathology Group, Vall d'Hebron Research Institute, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain. jazmine.arevalo@vhir.org.

Scientific reports
|November 9, 2023
PubMed
概括

在血清727 (pS727) 中对信号传感器和转录3激活剂 (STAT3) 的酸化促进了清细胞细胞癌 (ccRCC) 的发展. 这种pS727-STAT3激活驱动了前瘤表型,并确定了ccRCC的潜在生物标志物和治疗点.

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