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Updated: Jul 11, 2025

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes
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基于脂质液晶的持续释放配方的开发,以控制脱氧酸盐的释放:体外和体外评估

Maryam Kouhjani1, Arezoo Saberi1, Farzin Hadizadeh2,3

  • 1Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Science, Mashhad, Iran.

AAPS PharmSciTech
|November 9, 2023
PubMed
概括

一种新型的脂质液晶 (LLC) 配方的脱氧化 (NADC) 通过减少炎症和亡,有效地治疗蜂. 这种持续释放的NADC注射为美容手术提供了更安全的替代方案.

关键词:
脂质-液晶结晶的液体是什么脱氧化酸是一种脱氧化.通过光谱光计法方法.持续释放 持续释放 持续释放验证验证的时间

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Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
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Methods for Studying Drug Absorption: In vitro

In vitro experiments are crucial for understanding the transport and absorption of drugs through biological materials. These studies employ varied methods such as the diffusion cell method, the everted sac technique, and the everted ring technique.
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Theories of Dissolution: Diffusion Layer Model

Dissolution, the process by which drug particles dissolve in a solvent, is explained by the diffusion layer model, a theoretical framework that simulates the absorption of oral drugs and allows us to analyze experimental data.
This process starts with a thin layer, saturated with the drug, forming at the interface between the solid and liquid. The solute then diffuses from this layer into the main solution. The Noyes-Whitney equation suggests that the rate of dissolution relies on the diffusion...
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