英国生物银行的社会联系和死亡率:前性队列分析
Hamish M E Foster1, Jason M R Gill2, Frances S Mair3
1General Practice and Primary Care, School of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TB, Scotland. hamish.foster@glasgow.ac.uk.
BMC medicine
|November 10, 2023
概括
社会联系因素显著影响死亡风险. 独自生活与其他隔离标志物相结合,确定了一个高风险群体,强调需要进行全面评估.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 社会科学 社会科学 社会科学
背景情况:
- 社会联系与死亡率有关,但独立和联合效应需要进一步研究.
- 现有的研究往往缺乏对功能性和结构性社会联系组件的同时检查.
- 这项研究通过分析两种类型的社会联系及其与死亡率的关联来解决这一差距.
研究的目的:
- 研究功能性和结构性社会联系与所有原因和心血管疾病 (CVD) 死亡率的独立和联合关联.
- 为了确定特定的社会联系模式,赋予更高的死亡风险.
- 探索不同社会联系措施之间的潜在值效应和相互作用.
主要方法:
- 利用了来自458,146名参与者的英国生物库数据,与死亡登记簿相关联.
- 通过功能性 (信任,孤独) 和结构性 (访问,团体活动,独自生活) 措施来评估社会联系.
- 采用了Cox的比例危险模型来分析与所有原因和心血管疾病死亡率的关联,平均随访时间为12.6年.
主要成果:
- 所有社会联系措施独立预测死亡率.
- 观察到朋友/家人访问频率的门效应;每月访问次数低于增加死亡风险.
- 独自生活与访问频率和群体活动相互作用,增加死亡风险,特别是当与不经常的访问相结合时.
结论:
- 独自生活,特别是与其他结构隔离的指标,确定一个高风险人口的死亡率.
- 如果没有其他形式,一些社会联系的好处可能会减少.
- 功能性和结构性社会联系的综合评估对于识别死亡风险最大的个体至关重要.
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