亲素食饮食模式与结直肠癌风险之间的关联:一个匹配的病例对照研究
Elham Tavassoli Nejad1, Elham Moslemi2, Fateme Souni3
1Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
BMC research notes
|November 10, 2023
概括
坚持亲素食饮食模式 (PDP),以高摄入植物性食物和低肉类消费为特征,可显著降低患结肠直肠癌 (CRC) 的几率. 这一发现强调了以植物为中心的饮食在伊朗人口中对CRC的保护作用.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 关于植物性饮食与结直肠癌 (CRC) 发病率之间的关联的研究有限.
- 之前没有任何研究调查过亲素食饮食模式 (PDP) 和CRC之间的联系,无论是全球范围还是伊朗人口范围内.
研究的目的:
- 评估亲素食饮食模式 (PDP) 与结直肠癌 (CRC) 发病率之间的关联.
- 解决全球和伊朗研究中关于PDP和CRC风险的差距.
主要方法:
- 在伊朗德黑兰进行了一项基于医院的病例控制研究,包括71例病例和142例对照.
- 一个半定量的食物频率问卷评估了饮食摄入量,PDP指数是使用残留方法计算的,调整为总能量摄入量.
- 使用后勤回归分析来确定赔率比率 (ORs) 和95%置信区间 (CI),并根据混变量进行调整.
主要成果:
- 较高的PDP坚持与显著降低CRC的几率有关.
- 在原始和调整模型中,PDP的第3和第4个四分位数显示CRC几率与第1个四分位数相比显著降低 (调整后的OR从0.35到0.41).
结论:
- 该研究得出结论,一种亲素食饮食模式 (PDP),包括蔬菜,水果,谷物,乳制品和有限的肉类,与减少结肠直肠癌的几率有关.
- 坚持PDP可能会在伊朗人口中起到保护性作用,防止CRC.
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