白血病与中风后的第一年内失言症的恢复没有关联
Alexandra C Brito1, Deborah F Levy2, Sarah M Schneck2
1School of Medicine, Vanderbilt University, Nashville, TN, USA.
Neurobiology of language (Cambridge, Mass.)
|November 10, 2023
概括
白血病,中风后大脑健康的标志物,没有预测最初的语力衰竭的严重程度或恢复. 这一发现表明白质超强度可能不会影响中风后的言语和语言结果.
科学领域:
- 神经学 神经学
- 神经成像是一种神经成像.
- 脑卒中康复治疗 脑卒中康复治疗
背景情况:
- 脑卒中后的阿法西亚是常见的,恢复受到大脑存活组织的影响.
- 白血病 (白质强度过高) 表明大脑小血管疾病,与认知/运动缺陷有关.
- 之前关于白内障症作为失语恢复的预测因素的研究是不一致的.
研究的目的:
- 为了调查白血病和失言症的严重程度和中风后第一年恢复之间的关系.
- 为了确定白血病预测了最初的失语严重程度,恢复程度,或长期的结果.
主要方法:
- 招募了267名急性左半球中风患者.
- 使用液体减弱反转恢复 (FLAIR) MRI 来评估白血病.
- 评估了174名急性失言症患者,其中84人使用多变量回归模型评估了长期结果.
主要成果:
- 90%的患者有不同程度的白血病.
- 白血病的严重程度并不能预测最初的失语症的严重程度.
- 没有发现白血病和语障恢复或长期严重程度之间有显著的关系.
结论:
- 白血病在中风患者中非常普遍,但似乎不是对失言症结果的预测因素.
- 缺乏关联可能是由于大脑小血管疾病的解剖位置相对于关键的语音和语言通路.
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