Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Hematopoiesis01:21

Hematopoiesis

5.3K
The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...
5.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Risk factors for severe burn-related injuries among children and youth: a systematic review and meta-analysis.

Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention·2026
Same author

Combined family-based association and linkage analyses in families affected by attention-deficit hyperactivity disorder.

Human genetics·2026
Same author

Normative modeling for quantitative brain MRI phenotyping and biomarker discovery for pediatric leukodystrophies.

medRxiv : the preprint server for health sciences·2026
Same author

Enrichment of Fetal Cell-Free DNA in Early Miscarriages for Detection of Aneuploidy: A Novel Approach.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2026
Same author

Determinants of severe fall-related injuries among children and youth: a systematic review and meta-analysis.

Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention·2026
Same author

Association of Advanced Access With Primary Care Performance: A Systematic Review.

Annals of family medicine·2026

相关实验视频

Updated: Jul 11, 2025

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

842

挖掘差距:使用临床数据集来推导血液学参数的怀孕参考间隔.

Vilte E Barakauskas1,2, Mary Kathryn Bohn3, Emma Branch4

  • 1Department of Pathology and Laboratory Medicine, BC Children's and Women's Hospital, Vancouver, BC, Canada.

Clinical chemistry
|November 10, 2023
PubMed
概括

在怀孕期间确立完整血清 (CBC) 的准确参考间隔 (RI) 是至关重要的. 这项研究使用相关的实验室和注册表数据为加拿大母亲开发了新的妊娠特异性CBC RIs,突出了传统的基于三个月的评估的局限性.

更多相关视频

Methylation Specific Multiplex Droplet PCR using Polymer Droplet Generator Device for Hematological Diagnostics
09:05

Methylation Specific Multiplex Droplet PCR using Polymer Droplet Generator Device for Hematological Diagnostics

Published on: June 29, 2020

5.2K
Author Spotlight: Advancing Erythropoiesis Research - A Simplified Pipeline for Assessing Hematopoietic Stem Cell Function in Myelodysplastic Syndromes
08:53

Author Spotlight: Advancing Erythropoiesis Research - A Simplified Pipeline for Assessing Hematopoietic Stem Cell Function in Myelodysplastic Syndromes

Published on: January 10, 2025

501

相关实验视频

Last Updated: Jul 11, 2025

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

842
Methylation Specific Multiplex Droplet PCR using Polymer Droplet Generator Device for Hematological Diagnostics
09:05

Methylation Specific Multiplex Droplet PCR using Polymer Droplet Generator Device for Hematological Diagnostics

Published on: June 29, 2020

5.2K
Author Spotlight: Advancing Erythropoiesis Research - A Simplified Pipeline for Assessing Hematopoietic Stem Cell Function in Myelodysplastic Syndromes
08:53

Author Spotlight: Advancing Erythropoiesis Research - A Simplified Pipeline for Assessing Hematopoietic Stem Cell Function in Myelodysplastic Syndromes

Published on: January 10, 2025

501

科学领域:

  • 产科和妇科 产科和妇科
  • 临床病理学 临床病理学
  • 医疗信息学 医疗信息学

背景情况:

  • 怀孕期间的生理变化需要针对怀孕的实验室测试参考间隔,因为一般人群的参考间隔是无效的.
  • 现有的研究确定孕妇人群的RIs是有限的,特别是当代加拿大母亲.
  • 由于实验室信息系统 (LIS) 中缺乏易于获得的妊娠和健康状况数据,怀孕RI的回顾性推导具有挑战性.

研究的目的:

  • 为了得出完全血清 (CBC) 和差异化测试的回顾性怀孕特定参考间隔 (RIs).
  • 评估母亲和怀孕特征对CBC实验室值的影响.
  • 评估传统的基于三个月的RI与基于妊娠年龄的RI对孕妇的适用性.

主要方法:

  • 一项回顾性队列研究,利用来自不列颠哥伦比亚省周产期数据注册局和两个实验室的链接数据.
  • 一个5年健康怀孕队列的定义 (n=143,106个单期单期怀孕).
  • 使用直接和间接方法计算CBC和差异性RI,按三个月和妊娠周分析.

主要成果:

  • 分析了超过97.2万份CBC结果,并按三个月和妊娠周计算了RI.
  • 观察到的结果趋势与现有文献一致,但许多测试的特定RI极限不同.
  • 发现三季度特定的容器可能不适合快速变化的CBC参数,如红细胞,白细胞和血小板.

结论:

  • 将全面的临床数据库与LIS数据联系起来,提供了一种可靠的方法来导出妊娠RIs.
  • 传统的三分之一月纸箱对于在怀孕期间定义正常CBC值有局限性.
  • 这项研究支持使用妊娠年龄或经验上获得的数据来获得更准确的CBC参考值.