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20年的B型大动脉剖析经验:芬兰基于人口的国家注册表的研究
Juhana Mikael Toimela1, Jagdeep Sedha2, Marja Hedman1,3
1Department of Cardiothoracic Surgery, Kuopio University Hospital, Kuopio, Finland.
Interdisciplinary cardiovascular and thoracic surgery
|November 10, 2023
概括
斯坦福B型大动脉切割 (BTAD) 每年影响每10万芬兰人中有1.62人. 胸内血管大动脉修复 (TEVAR) 为BTAD患者提供了比医疗治疗或手术更好的生存率.
科学领域:
- 心血管外科心血管外科
- 血管外科 血管外科
- 公共卫生 公共卫生
背景情况:
- 斯坦福B型大动脉剖析 (BTAD) 是一个关键的心血管紧急情况.
- 了解人口水平的发病率,治疗模式和结果对于医疗保健规划至关重要.
研究的目的:
- 在芬兰人口中研究BTAD的发病率,治疗方法和存活率,长达20年的时间.
- 为了比较BTAD不同治疗策略的有效性.
主要方法:
- 追溯分析2000-2019年全国健康数据.
- 包括所有15岁以上的BTAD患者.
- 从死亡原因登记处获得的死亡率数据.
主要成果:
- 确诊了1742例BTAD病例,占所有大动脉切割的45.6%.
- 每年每10万居民的BTAD发病率为1.62.
- 平均存活时间:12.7年 (TEVAR),12.4年 (手术),8.6年 (医疗治疗). TEVAR和手术显示出比医疗治疗显著更好的生存率 (P < 0.001). 根据年龄调整的生存率与TEVAR (HR 0.578,P < 0.001) 最好. 与大动脉相关的死亡是死亡的主要原因 (41%).
结论:
- 芬兰BTAD发病率与国际数据一致.
- 胸内血管大动脉修复 (TEVAR) 与BTAD患者的生存率显著改善有关.
- 与大动脉相关的死亡的长期风险需要在BTAD幸存者中进行持续的监测和管理.
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