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Updated: Jul 11, 2025

Cryogenic Sample Loading into a Magic Angle Spinning Nuclear Magnetic Resonance Spectrometer that Preserves Cellular Viability
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固态NMR光谱检测冷溶液中的状态和相变

Yong Du1, Jinghan Li2, Wei Xu1

  • 1Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.

Molecular pharmaceutics
|November 10, 2023
PubMed
概括

固态核磁共振光谱 (ssNMR) 揭示了冷制药溶液中的结晶和特征溶液状态. 这为生物制药配方和工艺开发提供了关键的见解.

关键词:
生物制药生物制药公司化学转移是指化学转移的发生.结晶化 结晶化的过程.结缩缩剂可以冷.冷溶液的冷解决方案这就是histidine.它们的pH值为pH.固态NMR是一种固态NMR.同步 X射线衍光度测量

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