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Updated: Jul 11, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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MMPatho:利用多层次共识和进化信息进行增强的误解突变病原性预测

Fang Ge1,2, Muhammad Arif3,4, Zihao Yan5

  • 1School of Geographic and Biologic Information, Nanjing University of Posts and Telecommunications, 9 Wenyuanlu, Nanjing 210023, China.

Journal of chemical information and modeling
|November 10, 2023
PubMed
概括

我们开发了MMPatho,这是一个计算工具,用于预测误解突变 (MM) 病原性. MMPatho使用变异和蛋白质语言模型特征准确地识别引起疾病的突变,帮助遗传疾病研究.

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