纳米粒子在癌症治疗中的应用:简要的回顾
Mariana Sell1, Ana Rita Lopes2, Maria Escudeiro3
1Polytechnic Institute of Viseu, Av. Cor. José Maria Vale de Andrade, 3504-510 Viseu, Portugal.
Nanomaterials (Basel, Switzerland)
|November 10, 2023
概括
纳米技术通过改善药物输送和向来增强癌症治疗. 本综述涵盖了2010-2023年的纳米系统,详细介绍了各种纳米颗粒及其在癌症治疗和治疗术中的应用.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 在瘤学瘤学.
背景情况:
- 癌症仍然是全球主要的死亡原因,需要先进的治疗策略.
- 纳米技术在癌症治疗中提供了显著的优势,因为它可以提供有针对性的药物,并减少副作用.
- 纳米系统对于提高抗瘤疗法的有效性和安全性至关重要.
研究的目的:
- 提供2010年至2023年期间开发的用于癌症治疗的新型纳米系统的全面审查.
- 总结各种纳米粒子在癌症治疗中的设计,应用和向策略.
- 突出纳米技术在推进癌症治疗学方面的潜力.
主要方法:
- 2010-2023年关于纳米系统用于癌症治疗的科学成果的文献综述.
- 对纳米粒子设计,药物封装和瘤微环境相互作用的分析.
- 不同纳米粒子类别的比较,包括脂质体,聚合物纳米粒子,量子点,黄金纳米粒子,氧化铁纳米粒子和碳纳米材料.
主要成果:
- 纳米系统证明了药物递送的改善,毒性降低,以及对癌细胞的增强向.
- 诸如纳米脂质体,聚合物纳米粒子,量子点,黄金纳米粒子,氧化铁纳米粒子和碳纳米材料等各种纳米粒子在临床前和临床环境中表现有前途.
- 无论是被动的还是主动的准策略,对于有效的癌症治疗术来说都至关重要.
结论:
- 纳米技术为开发下一代癌症疗法提供了一个强大的平台.
- 对纳米系统的持续研究将大大推进向癌症治疗和神经科学.
- 审查的纳米粒子为改善癌症诊断和治疗提供了多种机制.
相关概念视频
02:57Targeted Cancer Therapies
7.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.7K
02:49Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K
02:50Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K