一个季节性的时钟适合所有?
Stephan Michel1, Laura Kervezee2
1Department of Cell and Chemical Biology, Leiden University Medical Center, Postzone S5-P, 2300 RC, PO Box 9600, Leiden, The Netherlands. S.H.Michel@lumc.nl.
概括
生物通过光周期调节适应季节性变化. 昆虫和哺乳动物的共同机制,包括昼夜系统和黑激素,突出了与人类季节节律相关的保存途径.
科学领域:
- 比较生理学比较生理学
- 时间生物学 时间生物学
- 环境适应环境适应
背景情况:
- 季节性适应对于生物的生存至关重要,大多数研究都集中在繁殖上.
- 人类在生理学,行为和疾病方面表现出年度节奏,尽管季节性环境影响最小.
- 气候变化需要了解由于环境条件变化的季节性适应机制.
研究的目的:
- 探索不同物种光周期调节的共同原则和机制.
- 突出昆虫和哺乳动物之间季节性适应的保护途径.
- 讨论这些机制对人类生理学和健康的相关性.
主要方法:
- 对昆虫和哺乳动物光周期调节机制的比较分析.
- 对参与季节性适应的信号分子 (VIP,PDF) 和激素 (黑激素) 的审查.
- 检查昼夜系统和神经递质功能在光周期反应中的作用.
主要成果:
- 昼夜系统在光周期调节中发挥作用.
- 分享的信号分子 (VIP,PDF) 和激素黑激素参与昆虫和哺乳动物的季节性适应.
- 光周期的变化会影响研究动物群体中的神经递质功能.
结论:
- 在昆虫和哺乳动物中存在保存的季节性适应机制.
- 了解这些保存的途径可以提供对人类季节性节奏和健康的见解.
- 鼓励对多种生物进行进一步的研究,以充分阐明季节性适应机制.
更多相关视频
07:42Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter
Published on: September 17, 2016
12.9K
07:44In Vivo Monitoring of Circadian Clock Gene Expression in the Mouse Suprachiasmatic Nucleus Using Fluorescence Reporters
Published on: July 4, 2018
8.3K
相关概念视频
Biological Clocks and Seasonal Responses
34.7K
The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
34.7K
Circadian Rhythms and Gene Regulation
4.1K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.1K
Global Climate Change
24.4K
Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
24.4K
