患有缺氧缺血性脑病变的婴儿急性损伤
Marwa M Elgendy1, Josef Cortez2, Firas Saker3
1Department of Pediatrics & Neonatology, University of Florida College of Medicine-Jacksonville, Jacksonville, FL, USA. Marwa.elgendy@jax.ufl.edu.
Pediatric nephrology (Berlin, Germany)
|November 10, 2023
概括
低毒性缺血性脑病变 (HIE) 显著增加了婴儿急性损伤 (AKI) 的风险. 严重的HIE构成最高风险,导致死亡率增加,强调需要对AKI进行警监测.
科学领域:
- 新生儿医学 新生儿医学
- 儿科脏病学 儿科脏病学
- 关键的护理关键的护理
背景情况:
- 缺氧性缺血性脑病变 (HIE) 是一个严重的出生并发症.
- 急性损伤 (AKI) 是患有HIE的婴儿的潜在并发症.
- 了解AKI的患病率和HIE的结果对于新生儿护理至关重要.
研究的目的:
- 确定不同程度的HIE婴儿中AKI的流行率.
- 调查HIE严重程度与AKI发病率之间的关联.
- 分析AKI对HIE婴儿死亡率和停留时间的影响.
主要方法:
- 使用了2010-2018年国家住院样本 (NIS) 数据库.
- 包括一个超过3100万婴儿的大队伍.
- 使用回归分析来控制混变量.
主要成果:
- 与没有HIE的婴儿相比,患有AKI的婴儿患病率明显更高 (9.0%) (0.04%).
- 严重的HIE与最高的AKI患病率 (19.7%) 和增加的死亡率有关.
- HIE婴儿的AKI与较高的死亡率 (28.9%与8.8%) 和更长的住院时间相关.
结论:
- 在新生儿中,HIE是发展AKI的强有力的危险因素.
- 患有严重HIE和AKI的婴儿面临着最高的死亡风险.
- 在HIE婴儿中早期发现和管理AKI对于改善结果至关重要.
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