在头部和部癌症的辐射后进行治疗后监测成像
Allen M Chen1, Jeremy P Harris1, Meng Gan1
1Department of Radiation Oncology, Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange.
JAMA network open
|November 10, 2023
概括
监测成像没有改善头癌患者缓解期的治疗结果. 对这些患者来说,预期的管理与化学辐射后的常规成像一样有效.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 相对有效性研究研究比较
背景情况:
- 由于证据有限,头癌治疗后监视成像的作用仍然存在争议.
- 对缓解期无症状患者的最佳后续策略尚不清楚.
研究的目的:
- 评估监视成像对无症状头癌患者的预期管理的有效性,这些患者在化学辐射治疗后实现了缓解.
主要方法:
- 340名头癌成年患者的回顾性评估,以及治疗后的完整代谢反应.
- 对接受监测成像 (PET/CT,MRI,CT) 和接受预期治疗 (临床随访) 的患者的结局进行比较.
主要成果:
- 监测成像和预期管理组之间在3年地方区域对照,总生存率或无进展生存率上没有显著差异.
- 两种管理策略之间,远程转移的自由度也相似.
结论:
- 基于成像的监测并没有证明,在缓解期的头癌患者中,与期望管理相比,结果有所改善.
- 在这种患者群体中,预期管理是例行监测成像的可行替代方案.
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