长期职业暴露对老年人的无残疾生存率和死亡率的影响
S M Alif1,2,3, G P Benke1, H Kromhout4
1School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria 3004, Australia.
Occupational medicine (Oxford, England)
|November 10, 2023
概括
长期职业接触灰尘和农药会对老年人的健康产生负面影响. 这种暴露与减少无残疾生存率和增加死亡率有关,特别是在男性中.
科学领域:
- 职业健康 职业健康 职业健康 职业健康
- 老年学是一门学科.
- 流行病学 流行病学
背景情况:
- 人口老龄化增加了长期职业暴露对老年人健康的相关性.
- 之前的研究还没有广泛研究职业暴露对这一人口群体无残疾生存的影响.
研究的目的:
- 研究长期职业暴露与无残疾生存率 (DFS) 之间的关联.
- 检查职业暴露与健康老年人所有原因和特定原因死亡率之间的关系.
主要方法:
- 在ASPREE研究中分析了12215名健康参与者的数据 (平均年龄75岁).
- 用ALOHA-plus JEM (工作暴露矩阵) 来评估职业暴露.
- 无残疾生存率 (DFS) 是主要终点,定义为无死亡,痴呆或持续身体残疾的生存率.
主要成果:
- 对尘埃和农药的不断高和累积暴露与减少DFS有关.
- 与未暴露的男性相比,暴露于灰尘和农药的男性显示DFS减少.
- 对溶剂 (男性) 和尘埃 (女性) 的高职业暴露与所有原因和癌症死亡率的增加有关.
结论:
- 对尘埃和农药的长期职业暴露与健康的老年人中减少DFS有关.
- 这些暴露还与社区老年人死亡率的增加有关.
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