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Updated: Jul 5, 2026

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一个基于mTBI临床概况的共同数据元素判断过程:一个有针对性的多领域临床试验初步研究

Kori J Durfee1, R J Elbin1, Alicia M Trbovich2

  • 1Office for Sport Concussion Research, University of Arkansas, Fayetteville, AR 72701, USA.

Military medicine
|November 10, 2023
PubMed
概括

这项研究发现,对偏头痛/头痛,前庭关节和焦虑/情绪的常见数据元素 (CDE) 对于识别轻度创伤性脑损伤 (mTBI) 概况是有用的. 在这项mTBI研究中,认知和眼部CDE的临床价值较低.

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Clinical Trials01:16

Clinical Trials

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Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Therapeutic Drug Monitoring: Affecting Factors

Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
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