一个随机对照试验精确营养咨询服务的服务成员有代谢综合征的风险
Mary S McCarthy1, Zachary T Colburn1, Ka Yee Yeung2
1Center for Nursing Science & Clinical Inquiry, Madigan Army Medical Center, Tacoma, WA 98431, USA.
Military medicine
|November 10, 2023
概括
基于DNA的营养咨询并没有显著减少军事人员的体重. 虽然观察到初步进展,但体重减轻在12周后没有持续,这表明这种干预措施在降低代谢综合征风险方面的有效性有限.
科学领域:
- 军人卫生保健 军人卫生保健
- 营养科学 营养科学
- 遗传学 是一个遗传学.
背景情况:
- 代谢综合征 (MetS) 对军事准备和健康构成重大威胁.
- 关键的危险因素包括高血压,低HDL胆固醇,高甘油三,腹部肥胖和高禁食血糖.
- 精准营养和健康应用程序显示,高参与度的体重管理具有前景.
研究的目的:
- 评估基于DNA的营养咨询在减少现役军人的MetS风险因素方面的有效性.
- 评估体重变化,生物标志物和遵守电子健康应用程序.
主要方法:
- 预期随机对照试验,有107名参与者完成了研究.
- 干预组接受了基于遗传测序和生物标志物的营养学家主导的咨询;对照组接受了小册子.
- 测量包括基线和12周的人类测量,血压和生物标志物;用于饮食和活动跟踪的eHealth应用程序.
主要成果:
- 在12周后,在不同组之间没有观察到显著的体重减轻.
- 甲状腺综合症的患病率从27%降至17.8%;与肥胖,胆固醇和高血压有关的遗传变异的高患病率.
- 低维生素D水平很常见,研究后有45%的维生素D水平不足;电子健康应用的遵守率很低.
结论:
- 基于DNA的营养咨询在这个军事人群中对减肥无效.
- 在6周观察到的初始体重减轻在12周没有持续.
- 需要进一步的研究,以优化军事健康的精密营养干预措施.
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