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南西托隆B调节内源性阿片类系统,促进小鼠的抗受体

Renan Fernandes do Espírito-Santo1, Dourivaldo Silva Santos2, Pedro Santana Sales Lauria2

  • 1Center to Advance Chronic Pain Research, University of Maryland, Baltimore, Maryland 21201, United States.

Journal of natural products
|November 10, 2023
PubMed
概括

植物衍生化合物Tonantzitlolone B (TZL-B) 有效地减少了没有运动障碍的小鼠的疼痛. 它通过增加preproenkephalin (PENK) 基因表达来调节内源性阿片类系统.

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