在Solanaceae中O-甲基转移酶 (OMT) 基因家族的演变和多样化
Pedro Henrique Pezzi1, Leonardo Tresoldi Gonçalves1, Maríndia Deprá1
1Universidade Federal do Rio Grande do Sul, Departamento de Genética, Porto Alegre, RS, Brazil.
Genetics and molecular biology
|November 10, 2023
概括
在Solanaceae中的O-甲基转移酶 (OMT) 基因家族通过重复事件扩大,导致植物生物学中的新功能. 这项研究阐明了OMT的演变及其生物技术潜力.
科学领域:
- 植物分子生物学 植物分子生物学
- 植物基因组学 植物基因组学
- 进化生物学是进化的生物学.
背景情况:
- 甲基转移酶 (OMT) 是植物二次新陈代谢中的重要酶,影响着木质素,色素和香味.
- 在Solanaceae家族中OMTs的进化历史和多样化并未得到充分理解.
研究的目的:
- 在六种Solanaceae物种中对OMT基因进行全面的全基因组分析.
- 阐明Solanaceae中OMT基因家族的进化途径和功能多样化.
主要方法:
- 在六种Solanaceae物种中对OMT基因进行全基因组调查.
- 遗传学分析用于重建基因进化关系.
- 对基因结构,染色体位置和重复事件的分析.
主要成果:
- 确定了57个咖啡-可亚OMTs (CCoAOMTs) 和196个咖啡酸OMTs (COMTs).
- 在染色体2上发现了保存的并联重复的OMT基因块.
- 将OMT基因家族扩展归因于全基因组,细分和并联重复,随后进行新功能化和子功能化.
结论:
- 在Solanaceae中OMT基因家族的扩张是多重重复机制的结果.
- 了解OMT进化提供了关于它们在植物生物过程中的作用的见解.
- 在Solanaceae中,OMTs代表了未来生物技术应用的重要目标.
更多相关视频
相关概念视频
Gene Duplication and Divergence
6.1K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
6.1K
Gene Families
8.8K
Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
8.8K
Overview of Transposition and Recombination
15.6K
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
15.6K
Evolutionary Relationships through Genome Comparisons
5.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.8K
Bacterial Transcription
28.3K
RNA polymerase (RNAP) carries out DNA-dependent RNA synthesis in both bacteria and eukaryotes. Bacteria do not have a membrane-bound nucleus. So, transcription and translation occur simultaneously, on the same DNA template.
Transcription can be divided into three main stages, each involving distinct DNA sequences to guide the polymerase. These are:
Transcription can be divided into three main stages, each involving distinct DNA sequences to guide the polymerase. These are:
28.3K
Cis-regulatory Sequences
9.9K
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
9.9K


