在丹麦和加拿大阿尔伯塔省的孕期糖尿病和妊娠前症的时间趋势,2005年至2018年 - 一项基于人口的队列研究
Frederikke Lihme1, Ana Savu2, Saima Basit1
1Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Acta obstetricia et gynecologica Scandinavica
|November 10, 2023
概括
在丹麦和阿尔伯塔省,2005年至2018年期间,孕前症和妊娠期糖尿病的患病率显著增加. 妊娠并发症的上升趋势需要增加医疗保健系统的支持.
科学领域:
- 生殖健康 生殖健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 孕前症和妊娠期糖尿病有共同的危险因素,如肥胖和晚年母亲的年龄.
- 这些风险因素在近几十年来变得越来越普遍,影响怀孕的结果.
研究的目的:
- 在丹麦和阿尔伯塔省从2005年至2018年检查孕前和妊娠期糖尿病患病率的趋势.
- 调查母亲年龄的变化,平价,多胎妊娠,并发症和BMI是否解释了这些趋势.
主要方法:
- 基于登记的队列研究,使用丹麦和阿尔伯塔的健康登记.
- 包括所有导致活产婴儿的怀孕在2005-2018年期间.
- 使用二项式回归来估计每年患病率的增加,根据母亲的特征进行调整.
主要成果:
- 孕前的患病率在丹麦从2.5%增加到2.9%,在阿尔伯塔省从1.7%增加到2.5%.
- 怀孕期糖尿病的患病率在丹麦从1.9%上升到4.6%,在阿尔伯塔省从3.9%上升到9.2%.
- 孕产妇年龄和BMI的变化有部分影响,但不能完全解释患病率的增加.
结论:
- 从2005年至2018年期间,观察到先兆子和妊娠期糖尿病患病率的显著增加.
- 这些上升趋势预测,在受影响的妇女中,慢性疾病的发病率将来会增加.
- 由于对长期随访护理的需求增加,医疗保健系统面临着更大的压力.
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