相关实验视频
Updated: Jul 11, 2025

12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
18.9K
慈善药物分发改善了对没有保险的糖尿病患者的护理
Jonathan Hughes1, Abby Sparkman, Priscilla Smith
1Ascension Saint Thomas Rutherford, 1700 Medical Center Pkwy, Murfreesboro, TN 37129.
The American journal of managed care
|November 10, 2023
概括
捐赠胰岛素显著改善了2型糖尿病 (T2D) 的未保险患者的血糖控制. 慈善药房改善了药物获取和治疗结果,使HbA1c水平降低了2.4%.
科学领域:
- 内分泌学 在内分泌学.
- 药物经济学 药物经济学
- 公共卫生 公共卫生
背景情况:
- 没有保险的2型糖尿病 (T2D) 患者在获得必需胰岛素药物方面面临重大障碍.
- 慈善药品分销商和合作药店在弥合这些获取差距方面发挥着至关重要的作用.
研究的目的:
- 评估捐赠胰岛素产品对未保险T2D患者药物获取和血糖控制的影响.
- 评估制药制造商,希望药房和社区药房之间的合作伙伴关系的有效性.
主要方法:
- 一项涉及无保险T2D患者的回顾性观察性研究规定了胰岛素.
- 数据收集包括基线和随访HbA1c水平,胰岛素填充史和患者辅助计划推.
- 分析的重点是HbA1c的变化和药物覆盖率.
主要成果:
- 在6个月内 (P=.033) 观察到平均HbA1c降低2.4个百分点 (从11.2%降至8.8%).
- 50%的参与者在6个月内达到HbA1c低于9%的水平.
- 显著的每月胰岛素成本节省从每名参与者183.74美元到253.84美元不等.
结论:
- 慈善合作伙伴提供的捐赠胰岛素显著改善了未保险T2D患者的血糖控制.
- 该模型展示了药房合作伙伴关系在改善弱势群体药物获取和健康结果方面发挥的关键作用.
相关概念视频
Diabetes: Management and Pharmacotherapy
290
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
290
Insulin: Dosing Regimen and Adverse Effects
184
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
184
Oral Hypoglycemic Agents: Biguanides and Glitazones
212
Biguanides, particularly metformin (Glucophage), are insulin sensitizers that enhance glucose uptake, thereby reducing insulin resistance. Unlike sulfonylureas, metformin doesn't prompt insulin secretion, which helps to curb hypoglycemia risk. Metformin is beneficial in treating conditions like polycystic ovary syndrome due to its insulin-resistance reduction capability. The drug's primary action involves curtailing hepatic gluconeogenesis, a significant contributor to high blood...
212
Drug Therapy
47
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
47
Insulin Formulations: Types and Delivery
205
Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
Short-acting insulins are divided into...
Short-acting insulins are divided into...
205
Drug Delivery: Miscellaneous Routes
359
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
359

