血清维生素B12度与老年人改善记忆有关,而老年人更坚持地中海饮食
Inés Domínguez-López1, Rosa Casas2, Gemma Chiva-Blanch3
1Polyphenol Research Group, Departament de Nutrició, Ciències de l'Alimentació i Gastronomía, Facultat de Farmacia, Universitat de Barcelon (UB), Av. de Joan XXII, 27-31, 08028 Barcelona, Spain; Institut de Nutrició i Seguretat Alimentària (INSA), Universitat de Barcelona (UB), 08921 Santa Coloma de Gramanet, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Clinical nutrition (Edinburgh, Scotland)
|November 10, 2023
概括
维生素B12可以提高老年人的记忆功能,但只有当他们密切遵循地中海饮食. 这种饮食还可以提高叶酸水平,这表明,除了基本营养之外,还有一种协同效应.
科学领域:
- 神经科学是一个神经科学.
- 营养科学 营养科学
- 老年学是一门学科.
背景情况:
- 维生素B12对于认知功能至关重要,可能受到叶酸等其他营养素的影响.
- 地中海饮食对认知健康和营养水平的影响需要进一步研究.
研究的目的:
- 评估维生素B12对认知表现的影响,与遵守地中海饮食有关.
- 为了确定地中海饮食是否影响血清叶酸和维生素B12水平.
主要方法:
- 在PREDIMED试验中的一项队列研究包括170名高风险参与者 (年龄在55-80岁).
- 采用14项调查问卷来衡量地中海饮食的坚持.
- 通过神经心理测试评估认知功能;量化血清维生素B12和叶酸.
主要成果:
- 血清维生素B12与地中海饮食高度坚持的参与者中的记忆功能有显著的相关性 (r2=0.57,P=0.028).
- 在依附度低的人群中观察到一个弱的逆相关性 (r2=0.37,P=0.731).
- 地中海饮食的坚持与血清叶酸有积极的关联,但与维生素B12无关.
结论:
- 在高心血管风险的老年人中,维生素B12对记忆力的积极影响与高度遵守地中海饮食有关.
- 这些发现表明,维生素B12的认知益处超出了其作为基本营养素的作用.
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