周围动脉疾病患者的多模式预康复 间歇性音-试验性随机对照试验
Miquel Coca-Martinez1, Elie Girsowicz2, Robert J Doonan3
1Division of Vascular Surgery, Department of Surgery, McGill University, Montreal, Quebec, Canada; Department of Anesthesia and Intensive Care, Universitat de Barcelona, Barcelona, Spain; Department of Anesthesia, McGill University, Montreal, Quebec, Canada.
Annals of vascular surgery
|November 10, 2023
概括
多模式预康复 (MP) 对于间歇性关节障碍患者来说是安全和可行的,改善了行走能力和生活质量. 需要进一步的试验来确认其在减少内血管再血管化 (ER) 需要的有效性.
科学领域:
- 血管外科 血管外科
- 康复医学 康复医学 康复医学
- 临床试验 临床试验
背景情况:
- 间歇性音显著影响患者的生活质量和功能能力.
- 内血管再血管化 (ER) 是一种常见的治疗方法,但预康复可能提供一种替代或补充的方法.
- 需要试点数据来评估多模式预康复 (MP) 的可行性,安全性和初步有效性.
研究的目的:
- 确定一个为期12周的多式预康复 (MP) 计划的可行性和安全性.
- 获取关于生活质量和功能性行走能力变化的试点数据.
- 探索MP对接受内血管再血管化 (ER) 的决定的影响.
主要方法:
- 试验性随机对照试验将12周的MP与50岁以上中度至严重间歇性音患者的标准护理 (无监督行走建议) 进行比较.
- MP包括监督炼,家庭炼,营养支持,戒烟和心理社会支持.
- 通过招聘/保留率评估可行性;通过不良事件评估安全性;通过6分钟步行测试和生活质量得分的变化评估有效性.
主要成果:
- 招聘和保留率分别为73%和92%,高度遵守MP组件 (70-90%).
- 与标准护理相比,MP组在功能能力 (6分钟步行测试) 和生活质量 (VascuQol) 中呈现出统计学上显著的改善.
- 没有报告任何不良事件;主要的坚持障碍包括疼痛和难以进行规定的炼.
结论:
- 多模式预康复 (MP) 是一种安全且可行的干预措施,用于间歇性关节障碍患者.
- 一个为期12周的MP计划显示了改善功能性行走能力和生活质量的承诺.
- 需要进行更大规模的试验来证实MP的有效性及其对ER率和长期结果的影响.
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