用不同的标准化和尺度特定的再表达方法对连续结果的元分析估计的变量.
Daniel Gallardo-Gómez1, Hugo Pedder2, Nicky J Welton2
1Department of Physical Education and Sports, Faculty of Education, University of Seville, 41013 Seville, Spain; Epidemiology of Physical Activity and Fitness Across the Lifespan Research Group (EPAFit), 41013 Seville, Spain.
Journal of clinical epidemiology
|November 10, 2023
概括
数据标准化方法对标准化平均差异 (SMD) 的元分析结果产生重大影响. 建议在标准化和再表达中使用一个单一的,规模特定的标准偏差 (SD) 参考,以最大限度地减少元分析中的偏差.
科学领域:
- 生物统计学 生物统计学
- 临床流行病学临床流行病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 使用标准化平均差异 (SMD) 的元分析对数据标准化和规模特定的再表达方法敏感.
- 标准化的选择影响了证据的综合,特别是在涉及老年人功能能力的临床试验中.
结论:
- 数据标准化方法为中小企业的元分析估计引入了变化.
- 建议使用单一的,规模特定的SD参考标准化,以防止偏见,而不是研究特定的聚合SDs.
- 建议将重新表达的SD引用与用于标准化的引用对齐,以确保一致的结果.
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