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CBAP调节了与Akt相关的TSC蛋白复合体的功能,以调节mTORC1信号传递

Wei-Ting Liao1, Yun-Jung Chiang2, Hsin-Fang Yang-Yen3

  • 1Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

The Journal of biological chemistry
|November 10, 2023
PubMed
概括

CBAP蛋白通过与AKT和TSC2相互作用来调节细胞生长,从而影响Rheb-mTORC1通路. 它的作用影响TSC1-TSC2稳定性和溶酶体转位,影响细胞增殖.

关键词:
标签: 活动 活动 活动在Rheb Rheb中,我们可以看到.细胞生长细胞的生长.在mTORC1激活过程中.小型的GTP酶.瘤细胞生物学

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